Can Hepatitis C Be Transmitted by Sharing Toothbrushes?
Guidelines for the prevention of hepatitis C virus (HCV) transmission often include a warning against sharing toothbrushes, razors, nail care equipment, and other personal items that potentially may come into contact with blood.
While studies definitively show that HCV can be transmitted by sharing needles and other equipment used for drug injection, the risk of sharing personal care articles is less clear.
German researchers performed a study to examine whether toothbrushes of HCV positive people are likely to be contaminated with the virus. The study included 30 participants with chronic hepatitis C. For each, 2 mL of saliva, collected before and after tooth brushing, plus toothbrush rinse water were tested for HCV RNA.
Results
Saliva collected before tooth brushing was positive for HCV RNA in 9 patients (30%).
Saliva collected after brushing the teeth had detectable HCV in 11 patients (36.7%).
12 toothbrush rinse water specimens (40%) tested positive for HCV RNA.
In 6 of these 12 patients, the "native" saliva (taken from the mouth) had been negative for HCV RNA.
Patients with detectable HCV RNA in their toothbrush rinse water showed no significant differences from those with negative rinse water with respect to clinical, biochemical, and virological parameters.

